The U.S. obesity epidemic is possibly the largest public health scourge our country has ever faced. So far, good news in the progress against this problem has been in short supply. Weight loss drugs may be changing that. In a society that has been at war with weight for decades, never have we seen drugs…
As GLP-1s have grown in popularity, there’s been an increasing amount of research into the drugs – sometimes highlighting potentially beneficial side effects but other times spotlighting troubling complications. A recent study in Physiology & Behavior falls into the latter category. Researchers concluded that GLP-1s – used for weight loss and to treat diabetes and…
Cancer patients often experience weight loss associated with cachexia, which can significantly impact the effectiveness of cancer treatments. That includes treatments such as immunotherapy and CAR T-cell therapy. A recent study showed that preventing weight loss can make treatments more effective. The study, published in the journal Blood Advances, found that cancer patients who lost…
The heart muscle faces a silent threat in patients with cancer and other chronic diseases: a life-threatening condition called cachexia. This debilitating syndrome, characterized by severe weight loss and muscle wasting, can extend its insidious reach beyond skeletal muscles, significantly impacting the very fabric of the heart. As cachexia progresses in some patients, the muscles…
The recent market reaction to the trial results of Novo Nordisk’s next-generation weight loss drug highlights a dangerous trend: the overemphasis on losing a significant number of pounds as the sole measure of success. Company executives earlier had predicted on investor calls that the medication, CagriSema could result in weight loss of at least 25%….
We’ve written about the significant toll cachexia can take on adults. But the life-threatening syndrome, characterized by the progressive loss of muscle mass and fat, can have a far more pronounced impact on children. Cachexia, often called “failure to thrive” in children, is associated with chronic illnesses such as cancer. But even if the underlying…
Cachexia is a devastating condition for those suffering from it and for their caregivers. But it’s also taking a toll on Medicare. Cachexia – a syndrome characterized by weight loss that affects many people with cancer and other chronic diseases — is tied to increased hospital admissions, longer hospital stays and a greater need for intensive…
NORTHBROOK, Ill., Dec. 20, 2024 /PRNewswire/ A peptide called TCMCB07 will be administered to patients who are diagnosed with stage 4 metastatic colorectal cancer and will undergo chemotherapy. Endevica Bio, a privately held company developing first-in-class peptide drug candidates, today announced the start of a Phase 2 clinical trial of its experimental drug TCMCB07 (B07) to prevent…
GLP-1 receptor agonists have become the go-to treatment for individuals struggling with obesity. While these medications have proven effective in aiding weight loss, they come with certain drawbacks. One of the most significant is the need to inject the medication, which can be inconvenient and even daunting for some patients. This can lead to poor…
GLP-1 drugs for weight loss have become popular because they’re very effective. But there are some significant risks that may not be readily apparent to patients — most notably the potential for muscle loss. GLP-1s helps regulate blood sugar levels, appetite and satiety. This class of drugs enhances insulin secretion, suppresses glucagon release, slows gastric…